Atorvastatin

Atorvastatin

Drug Details

Atorvastatin (generic name: atorvastatin calcium) is a prescription medication classified as a statin (HMG-CoA reductase inhibitor). It is commonly used to treat high cholesterol and to prevent cardiovascular disease. It works by inhibiting an enzyme involved in the production of cholesterol in the liver, thereby lowering LDL (bad cholesterol) and triglycerides, and increasing HDL (good cholesterol).

It is available as oral tablets under brand names such as Lipitor.

Use Details

This medication helps manage lipid levels and reduce the risk of heart-related events. It is approved for:

Approved Uses:

• Hypercholesterolemia
• Prevention of cardiovascular disease in high-risk individuals

Off-Label Uses:

• Diabetic dyslipidemia
• Post-stroke prevention

Dosage

• Adult: 10–80 mg once daily
• Children: 10–20 mg daily (in select pediatric patients)
• Route: Oral
• Adjustments: Use with caution in hepatic impairment; not recommended in active liver disease

Side Effects

Common:
– Muscle pain
– Diarrhea

Serious:
– Rhabdomyolysis
– Liver enzyme abnormalities

Seek immediate help if: You experience unexplained muscle pain, dark urine, or signs of liver problems like jaundice.

Pregnancy / Breastfeeding

Atorvastatin is classified as Pregnancy Category X. It should not be used during pregnancy or breastfeeding. It may cause harm to an unborn baby. Always consult your doctor.

Drug Interactions

Interacts with: antifungals, antibiotics (e.g., clarithromycin), HIV medications. Avoid combining with: grapefruit juice. Reason: increased risk of side effects due to altered metabolism.

Other Information

• Store at room temperature away from moisture and heat
• Black-box warning: None
• Prescription status: Prescription only

FAQs

What should I do if I miss a dose?
Take it when remembered; skip if near the next dose.

What happens if I overdose?
Seek emergency help immediately.

Can I drive after taking it?
Yes, unless you experience side effects like dizziness.

Is alcohol safe with this drug?
Limit alcohol; it may increase liver risks.

How quickly does it start working?
Within 2 weeks; full effect in 4–6 weeks.

Are there natural alternatives?
Diet, exercise, and supplements like red yeast rice may help but consult a doctor first.

Is Atorvastatin addictive?
No